Biologics in practice
نویسندگان
چکیده
منابع مشابه
Clinical effectiveness of biologics in clinical practice
TNF inhibitors are currently considered both effective and cost-effective in patients with active rheumatoid arthritis (RA), particularly in patients who have not responded fully to methotrexate. There is substantial doubt about the cost-effectiveness of TNF inhibitors as initial treatment for active RA. New data from the National Data Bank for Rheumatic Diseases now question the current consen...
متن کاملBiologics in organ transplantation.
The last two decades have witnessed a pandemic in antibody development, with over 600 entering clinical studies and a total of 28 approved by the FDA and European Union. The incorporation of biologics in transplantation has made a significant impact on allograft survival. Herein, we review the armamentarium of clinical and preclinical biologics used for organ transplantation--with the exception...
متن کاملBiologics in Dermatology
Skin and subcutaneous diseases affect millions of people worldwide, causing significant morbidity. Biologics are becoming increasingly useful for the treatment of many skin diseases, particularly as alternatives for patients who have failed to tolerate or respond to conventional systemic therapies. Biological therapies provide a targeted approach to treatment through interaction with specific c...
متن کاملBiologics in Rheumatology 2012
The term biologics have been used as a collective term for biological therapies. Therapeutic agents with biologic properties, including monoclonal antibodies and soluble cytokine receptors have been in use against rheumatic diseases for some time now. Treatment of rheumatic diseases has undergone a remarkable change over the last 10 years. This can be credited to an increased understanding of t...
متن کاملPrevalence of biologics monotherapy in a cohort of patients with Rheumatoid Arthritis in daily clinical practice
BACKGROUND Real-life registry data reveal approximately one-third of patients taking biologic agents use them as monotherapy, in spite that combination therapy with Disease Modifying Drugs is more efficacious than monotherapy. The aim of our study was to assess the prevalence of biologics monotherapy in a cohort of patients with RA followed at a single center, and to analyze the reasons for mon...
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ژورنال
عنوان ژورنال: Annals of Allergy, Asthma & Immunology
سال: 2016
ISSN: 1081-1206
DOI: 10.1016/j.anai.2016.05.021